A Morbilliform Variant of Vancomycin-Induced Linear IgA Bullous Dermatosis

A morbilliform variant of vancomycin-induced linear IgA bullous dermatosis.

BACKGROUND Linear IgA bullous dermatosis is an autoimmune blistering disease characterized clinically by the presence of small tense blisters and immunologically by the presence of IgA at the dermal-epidermal junction. Idiopathic, systemic disease-related, and drug-related versions of this disorder have been described, with the latter most commonly associated with vancomycin. OBSERVATIONS We ...

[Vancomycin-induced linear IgA bullous dermatosis].

Vancomycin-induced Linear Iga Bullous Dermatosis with Isomorphic Response

Linear IgA bullous dermatosis (LABD) is occasionally induced by certain drugs, of which vancomycin is the most common. We herein describe a case of vancomycin-induced LABD on the trunk and extremities. Our case was unique in which tense bulla was induced on the old operation scars. A 92-year-old man developed diffuse erythema and bullas on his trunk and extremities. Also, blister formation was ...

Linear IgA Bullous Dermatosis

Figure 1. Clinical photograph of linear IgA bullous dermatosis showing tense bullae and erosions involving the lower abdomen, inner thighs, and extremities.

[Drug induced linear IgA bullous dermatosis].

Linear IgA disease is an autoimmune subepidermal bullous disease in which linear IgA deposits are found at the basement membrane zone. It is classically idiopathic but a drug-induced variant seems to be individualized in which cutaneous lesions resolve spontaneously after cessation of responsible treatment. Among the commonly implicated drugs, vancomycin is the most frequently reported. One sho...